• Early empirical antibiotics and adverse clinical outcomes in infants born very preterm: A population-based cohort 

      Vatne, Anlaug; Hapnes, Nina; Stensvold, Hans Jørgen; Dalen, Ingvild; Guthe, Hans Jørgen Timm; Støen, Ragnhild; Brigtsen, Anne Karin; Rønnestad, Arild Erland; Klingenberg, Claus Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-28)
      Objective The objective of this study was to evaluate the association between empirical antibiotic therapy in the first postnatal week in uninfected infants born very preterm and the risk of adverse outcomes until discharge.<p> <p>Study design Population-based, nationwide registry study in Norway including all live-born infants with a gestational age <32 weeks surviving first postnatal week without ...
    • Prophylactic Oropharyngeal Surfactant for Preterm Newborns at Birth: A Randomized Clinical Trial 

      Murphy, Madeleine C.; Miletin, Jan; Klingenberg, Claus Andreas; Guthe, Hans Jørgen Timm; Rigo, Vincent; Plavka, Richard; Bohlin, Kajsa; Barroso Pereira, Almerinda; Juren, Tomáš; Alih, Ekele; Galligan, Marie; O'Donnell, Colm P. F. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-11)
      Importance - Preterm newborns at risk of respiratory distress syndrome are supported with continuous positive airway pressure (CPAP). Many newborns worsen despite CPAP and are intubated for surfactant administration, an effective therapy for treatment of respiratory distress syndrome. Endotracheal intubation is associated with adverse effects. Pharyngeal administration of surfactant to preterm animals ...